Richard J Johnson Selected Research

Hypoxia (Hypoxemia)

4/2023	Osthole Prevents Heart Damage Induced by Diet-Induced Metabolic Syndrome: Role of Fructokinase (KHK).
1/2023	Fructose might be a clue to the origin of preeclampsia insights from nature and evolution.
1/2023	Responses to Hypoxia: How Fructose Metabolism and Hypoxia-Inducible Factor-1a Pathways Converge in Health and Disease.
1/2021	Endogenous Fructose Metabolism Could Explain the Warburg Effect and the Protection of SGLT2 Inhibitors in Chronic Kidney Disease.
12/2020	Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes.
11/2019	Carbonic Anhydrase Inhibitors for the Treatment of High-Altitude Hypoxemia.
1/2018	Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice.
6/2010	Could uric acid be a modifiable risk factor in subjects with pulmonary hypertension?
3/2008	Pathogenesis of essential hypertension: historical paradigms and modern insights.
10/2004	Differential regulation of VEGF by TGF-beta and hypoxia in rat proximal tubular cells.

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Richard J Johnson Research Topics

Disease

123	Hypertension (High Blood Pressure) 11/2023 - 11/2001
69	Hyperuricemia 02/2023 - 06/2002
68	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2023 - 12/2005
66	Inflammation (Inflammations) 01/2024 - 10/2002
61	Chronic Renal Insufficiency 05/2024 - 04/2002
54	Obesity 12/2023 - 12/2005
38	Proteinuria 05/2023 - 10/2001
34	Fibrosis (Cirrhosis) 01/2024 - 07/2001
34	Insulin Resistance 04/2023 - 12/2005
33	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 06/2003
26	Kidney Diseases (Kidney Disease) 04/2023 - 10/2007
25	Gout 01/2021 - 06/2002
22	Dehydration (Water Stress) 05/2024 - 02/2010
21	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 07/2009
21	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 01/2007
21	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019 - 01/2003
20	Essential Hypertension 08/2023 - 09/2003
18	Fatty Liver 01/2023 - 02/2010
17	Vascular Diseases (Vascular Disease) 09/2013 - 06/2002
15	Non-alcoholic Fatty Liver Disease 11/2023 - 06/2008
15	Albuminuria 12/2020 - 01/2005
13	Type 2 Diabetes Mellitus (MODY) 12/2023 - 02/2009
12	Hypoxia (Hypoxemia) 04/2023 - 06/2002
11	Nephrotic Syndrome (Syndrome, Nephrotic) 08/2022 - 10/2002
10	Hypertriglyceridemia 02/2021 - 03/2006
10	Dyslipidemias (Dyslipidemia) 03/2020 - 11/2006
9	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 05/2023 - 11/2009
9	Glomerulonephritis 01/2021 - 04/2003
8	Ischemia 01/2023 - 05/2003
7	Pre-Eclampsia (Preeclampsia) 01/2023 - 02/2004
7	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 11/2012
6	Neoplasms (Cancer) 11/2023 - 12/2002
6	Kidney Calculi (Kidney Stone) 02/2023 - 09/2011
6	Tumor Lysis Syndrome 01/2023 - 10/2009
6	Chronic Kidney Failure (Chronic Renal Failure) 03/2018 - 04/2005
6	Diabetes Mellitus 01/2018 - 11/2006
5	Chronic Kidney Diseases of Uncertain Etiology 01/2024 - 01/2016
5	Hypertrophy 04/2023 - 03/2002
5	Starvation 09/2021 - 01/2009
5	Atherosclerosis 11/2020 - 01/2003
5	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019 - 01/2005
5	Hyperinsulinism (Hyperinsulinemia) 11/2016 - 12/2005
5	Arteriolosclerosis 09/2013 - 03/2005
4	Myocardial Infarction 01/2022 - 01/2005
4	Hyperglycemia 02/2021 - 10/2007
4	Body Weight (Weight, Body) 02/2021 - 11/2008

Drug/Important Bio-Agent (IBA)

180	Uric Acid (Urate)IBA 04/2023 - 06/2002
100	FructoseIBA 05/2024 - 12/2005
42	SaltsIBA 05/2024 - 11/2001
35	CreatinineIBA 12/2023 - 12/2002
34	SugarsIBA 05/2024 - 10/2007
30	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 03/2006
25	Allopurinol (Remid)FDA LinkGeneric 10/2020 - 06/2002
24	fructokinaseIBA 10/2023 - 06/2008
22	Proteins (Proteins, Gene)FDA Link 10/2023 - 04/2002
19	SodiumIBA 01/2023 - 06/2002
19	Urate Oxidase (Uricase)IBA 10/2022 - 12/2002
16	AlbuminsIBA 12/2023 - 11/2008
16	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 10/2001
16	Angiotensin IIIBA 11/2014 - 11/2001
15	Insulin (Novolin)FDA Link 10/2023 - 03/2006
13	Oxonic AcidIBA 12/2019 - 06/2002
12	Xanthine OxidaseIBA 01/2020 - 12/2002
11	Biomarkers (Surrogate Marker)IBA 05/2024 - 12/2004
11	EnzymesIBA 10/2023 - 06/2008
11	Vasopressins (Vasopressin)IBA 01/2023 - 01/2014
10	Adenosine Triphosphate (ATP)IBA 10/2023 - 07/2010
10	polyolIBA 10/2023 - 01/2014
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2013 - 07/2001
9	CarbohydratesIBA 10/2023 - 10/2007
9	High Fructose Corn SyrupIBA 01/2023 - 03/2006
9	Sucrose (Saccharose)IBA 01/2019 - 02/2010
8	Triglycerides (Triacylglycerol)IBA 04/2023 - 04/2008
8	C-Reactive ProteinIBA 08/2017 - 12/2005
8	AntioxidantsIBA 01/2015 - 01/2006
7	CollagenIBA 01/2024 - 02/2003
7	LipidsIBA 01/2021 - 01/2011
7	Aldehyde Reductase (Aldose Reductase)IBA 01/2019 - 01/2013
7	Messenger RNA (mRNA)IBA 04/2011 - 04/2002
6	Oxygen (Dioxygen)IBA 12/2023 - 01/2020
6	Urea (Carbamide)FDA LinkGeneric 04/2023 - 10/2001
6	DiureticsIBA 01/2023 - 07/2004
6	Blood Glucose (Blood Sugar)IBA 05/2020 - 10/2007
5	Phosphates (Orthophosphate)IBA 04/2023 - 11/2006
5	purineIBA 01/2021 - 12/2006
5	HDL CholesterolIBA 01/2018 - 06/2010
5	Drinking WaterIBA 01/2015 - 05/2005
5	NitrogenIBA 01/2013 - 10/2001
5	OsteopontinIBA 01/2012 - 03/2002
5	Transforming Growth Factor beta (TGF-beta)IBA 10/2005 - 06/2002
5	ReninIBA 03/2005 - 09/2002
4	Silicon Dioxide (Silica)FDA LinkGeneric 01/2024 - 01/2020
4	AntigensIBA 01/2023 - 08/2005
4	Oxidants (Oxidizing Agents)IBA 10/2022 - 04/2004
4	NucleotidesIBA 01/2021 - 01/2012
4	LeptinIBA 01/2021 - 11/2008
4	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 03/2020 - 01/2018

Therapy/Procedure

28	Therapeutics 01/2021 - 01/2003
6	Nephrectomy 01/2009 - 12/2002
4	Kidney Transplantation 12/2020 - 10/2018